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Let's learn about
IBOGAINE
12-methoxyibogamine · the iboga alkaloid
Iboga plant - orange fruit and green leaves
AKA iboga, eboga, the root bark
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What is it?
Iboga fruit beside a human brain
Ibogaine is a
non-classic psychedelic
An alkaloid from the Central African iboga shrub (Tabernanthe iboga). It acts on many brain systems at once - serotonin, dopamine, and opioid receptors among them - and is studied for its ability to interrupt addiction.
Comes as iboga root bark, or purified ibogaine in capsulesTaken swallowed - and it belongs under medical supervision because of the heart risk
AncientBwiti ritual
1962Anti-addiction
1970Banned
2024Studied
TodayTrials
What does the
research show?
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Studied to interrupt opioid addiction
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Eased PTSD & depression in veteran studies
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May reduce cravings & withdrawal
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Early research in trauma & brain injury
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How it unfolds
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Before
Screening & ECG
Medical screening and an ECG come first. With ibogaine, supervision is everything.
Visions
Life review
Body load
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Quick check
A friend wants to take ibogaine at home to quit opioids, with no medical check. What's safest?
Harm reduction
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Get a full cardiac screening and ECG first - ibogaine can cause dangerous heart-rhythm changes
Only in a medically supervised setting with emergency care on hand
Share your full health history and every medication - heart and liver conditions raise the risk
Never mix with opioids, stimulants, or other drugs - combinations can be deadly
Plan for a long journey - a day or more - and real integration support after
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What are the risks?
Dangerous heart-rhythm changes (QT prolongation) - deaths have occurred
Much higher risk with heart conditions or other drugs
Nausea, vomiting, tremors, and loss of coordination
Seizures - and, in rare cases, psychosis
A narrow margin between an effective and a dangerous dose
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Most reported deaths involve heart complications, pre-existing conditions, or mixing with other drugs - which is why screening and monitoring matter so much. Ibogaine is not a do-it-yourself medicine.

Where it stands
Ibogaine's legal map is just beginning to shift
ISchedule I - illegal in the U.S. except in approved research
$50MTexas became the first U.S. state to fund ibogaine trials (2025)
fewcountries (e.g. Mexico, New Zealand) allow supervised use abroad - rules vary widely
Myth or fact?
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Go back anytime to revisit. Knowing the risks - especially the cardiac ones - keeps you and the people around you safer.

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You finished Ibogaine 101. Knowing the risks - especially the cardiac ones - keeps you and your people safer.
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Sources
psychedelics.berkeley.edu · Nature Medicine · Stanford Medicine
dancesafe.org · psychedelicalpha.com · gov.texas.gov
Portal is an IRS-recognized 501(c)(3) nonprofit, and this is harm-reduction education central to our mission - not medical or legal advice, and never an endorsement to use any drug. We do not encourage or promote using any substance. Ibogaine is Schedule I in the U.S. and carries serious cardiac risks - never take it without medical screening and supervision. In an emergency, call 911. Need support during or after a psychedelic experience? The Fireside Project peer-support line: 62-FIRESIDE (623-473-7433), free and confidential.
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